The p38 MAP Kinase Project

The p38 MAP kinase is activated in response to cellular stress, such as stimulation by LPS. A series of compounds, known as pyridinyl-imidazoles, can inhibit the p38-mediated production of pro-inflammatory cytokines (TNF and IL-1) in response to LPS stimulation. These compounds are highly specific against the p38 MAP kinase.

Major findings from this project

Publications from this project

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