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Liang Tong Lab at Columbia University

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Research
Enzymes Involved in Fatty Acid/Carbohydrate Metabolism Acetyl-CoA Carboxylase (ACC) Propionyl-CoA Carboxylase (PCC) Methylcrotonyl-CoA Carboxylase (MCC) Pyruvate Carboxylase (PC) Carnitine acyltransferases AMP-activated Protein Kinase (AMPK/SNF1) ATP-citrate Lyase (ACLY) Malic Enzyme (ME)
Proteins Involved in mRNA Processing and/or Pol II Transcription Canonical pre-mRNA 3'-end Processing Histone pre-mRNA 3'-end Processing 5'-3' Exoribonucleases (XRNs) A Novel Quality Control Mechanism for 5'-end Capping
Additional Projects Cyclic di-AMP Signaling Separase Enzymes Involved in NAD Metabolism Crystallography Method/Software Development
Previous Projects Toll/Interleukin-1 Receptor (TIR) Domain BEACH Domain HCMV Protease
p38 MAP Kinase SH2 Domain HIV-2 Protease Human Renin Sindbis Virus Capsid Protein Human ras p21
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Replace (with GLRF) COMO Ghkl Patsol Download COMO and Replace
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Replace

REPLACE is a suite of programs for molecular replacement calculations. It currently consists of two major programs, GLRF for rotation function calculations and TF for translation function calculations. In addition, a small program (ANGCAL) is a convenient tool for conversions between angles and matrices.

The original documentations to GLRF and TF are written in TeX. The HTML versions are provided here for convenience, although many formatting and most of the math equations have not been properly included yet. For complete (and up to date) documentations, refer to the TeX and PostScript versions included with the program distribution. The PDF files for the original documentation can be downloaded here: GLRF and TF.

GLRF, The Rotation Function Program

TF, The Translation Function Program

This material is based upon work supported by the National Science Foundation under Grant No. DBI-9876668

Any opinions, findings and conclusions or recomendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation (NSF).

© copyright 1998-2002 by Liang Tong.